Sep 9, 1999 · These events are mediated by NGF as a result of binding to its two cell-surface receptors, TrkA and p75. TrkA is a receptor with tyrosine kinase ...
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The extracellular region of the nerve growth factor (NGF) receptor, TrkA, contains two immunoglobulin (Ig)-like domains that are required for specific ...
Jul 1, 1997 · NGF binds with high affinity to the extracellular region of the tyrosine kinase receptor TrkA. This domain comprises leucine and cysteine rich ...
The extracellular domains of the TrkA nerve growth factor (NGF) receptor and its homologs harbor a modular mosaic of potential ligand binding motifs, ...
Jan 4, 2007 · Nerve growth factor engages two structurally distinct transmembrane receptors, TrkA and p75, which have been proposed to create a ...
Nerve growth factor (NGF) is a neurotrophin that induces neuritogenic and trophic signals by binding to TrkA and/or p75 receptors. We report a comparative ...
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COMPLEX / TRKA RECEPTOR / NERVE GROWTH FACTOR / CYSTEINE KNOT / IMMUNOGLOBULIN LIKE DOMAIN / NERVE GROWTH FACTOR-TRKA COMPLEX COMPLEX. Function / homology.
Nov 18, 2015 · Background. Tropomyosin-related kinase A (TRKA) is a nerve growth factor (NGF) receptor that belongs to the tyrosine kinase receptor family.
Mar 17, 2000 · In this study, a minimum set of residues in the human TrkC second immunoglobulin-like domain, which does not bind nerve growth factor (NGF), ...
Summary. Nerve growth factor (NGF) induces neurite outgrowth and promotes survival of embryonic sensory and sympathetic neurons. TRKA, a receptor tyrosine ...